Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Frontier Airlines

The cheapest airline(s) flying from Santa Ana to Chicago is Frontier Airlines.

  • Frontier Airlines Frontier Airlines
  • American Airlines American Airlines
  • United Airlines United Airlines
  • Southwest Airlines Southwest Airlines
  • Alaska Airlines Alaska Airlines
  • Spirit Airlines Spirit Airlines
  • Hawaiian Airlines Hawaiian Airlines
Cheapest Month June

Travel Period: May 2025 - April 2026

The cheapest month(s) to fly from Santa Ana to Chicago is June.

  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
  • Jan 2026
  • Feb 2026
  • Mar 2026
  • Apr 2026
Cheapest Day of the Week Monday

The cheapest day(s) of the week to fly from Santa Ana to Chicago is Monday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Wed, 2 Apr, 2025

  • Time Earliest
    • Earliest
    • Latest
  • Depart Earliest
    • Earliest
    • Latest
  • Arrive
    • Earliest
    • Latest
  • Duration
    • Shortest
    • Longest
  • Stopover
    All
  • Airline Filter by Airline
    View All Airline
  • Availability
    • M
    • T
    • W
    • T
    • F
    • S
    • S
  • 07:00 SNA
    13:10 ORD
    4Hrs, 10m Direct
  • SNASanta Ana John Wayne Airport 07:00 - ORD 13:10 4h 10m Direct
  • SNASanta Ana John Wayne Airport 07:00
  • ORDChicago O'Hare International Airport 13:10
  • 4h 10m
  • Direct
  • United Airlines (UA 1634)Boeing 737 Max 8 Passenger
  • United Airlines (UA 1634)
    • M
    • T
    • W
    • T
    • F
    • S
    • -
  • Boeing 737 Max 8 Passenger
  • 07:45 SNA
    13:40 ORD
    3Hrs, 55m Direct
  • SNASanta Ana John Wayne Airport 07:45 - ORD 13:40 3h 55m Direct
  • SNASanta Ana John Wayne Airport 07:45
  • ORDChicago O'Hare International Airport 13:40
  • 3h 55m
  • Direct
  • American Airlines (AA 2590)Boeing 737 Max 8 Passenger
  • American Airlines (AA 2590)
    • M
    • T
    • W
    • T
    • -
    • -
    • -
  • Boeing 737 Max 8 Passenger
  • 07:45 SNA
    13:59 ORD
    4Hrs, 14m Direct
  • SNASanta Ana John Wayne Airport 07:45 - ORD 13:59 4h 14m Direct
  • SNASanta Ana John Wayne Airport 07:45
  • ORDChicago O'Hare International Airport 13:59
  • 4h 14m
  • Direct
  • American Airlines (AA 2590)Boeing 737 800
  • American Airlines (AA 2590)
    • -
    • -
    • -
    • -
    • F
    • -
    • -
  • Boeing 737 800
  • 07:45 SNA
    13:49 ORD
    4Hrs, 04m Direct
  • SNASanta Ana John Wayne Airport 07:45 - ORD 13:49 4h 04m Direct
  • SNASanta Ana John Wayne Airport 07:45
  • ORDChicago O'Hare International Airport 13:49
  • 4h 04m
  • Direct
  • American Airlines (AA 2590)Boeing 737 Max 8 Passenger
  • American Airlines (AA 2590)
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • Boeing 737 Max 8 Passenger
  • 08:50 SNA
    16:00 MDW
    5Hrs, 10m Direct
  • SNASanta Ana John Wayne Airport 08:50 - MDW 16:00 5h 10m Direct
  • SNASanta Ana John Wayne Airport 08:50
  • MDWChicago Midway Airport 16:00
  • 5h 10m
  • Direct
  • Southwest Airlines (WN 2380)Boeing 737 700
  • Southwest Airlines (WN 2380)
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • Boeing 737 700
  • 08:55 SNA
    14:55 ORD
    4Hrs, 00m Direct
  • SNASanta Ana John Wayne Airport 08:55 - ORD 14:55 4h Direct
  • SNASanta Ana John Wayne Airport 08:55
  • ORDChicago O'Hare International Airport 14:55
  • 4h
  • Direct
  • American Airlines (AA 2590)Boeing 737 Max 8 Passenger
  • American Airlines (AA 2590)
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • Boeing 737 Max 8 Passenger
  • 10:49 SNA
    16:54 ORD
    4Hrs, 05m Direct
  • SNASanta Ana John Wayne Airport 10:49 - ORD 16:54 4h 05m Direct
  • SNASanta Ana John Wayne Airport 10:49
  • ORDChicago O'Hare International Airport 16:54
  • 4h 05m
  • Direct
  • United Airlines (UA 2075)Boeing 737 Max 8 Passenger
  • United Airlines (UA 2075)
    • M
    • T
    • W
    • T
    • F
    • S
    • S
  • Boeing 737 Max 8 Passenger
  • 11:33 SNA
    17:36 ORD
    4Hrs, 03m Direct
  • SNASanta Ana John Wayne Airport 11:33 - ORD 17:36 4h 03m Direct
  • SNASanta Ana John Wayne Airport 11:33
  • ORDChicago O'Hare International Airport 17:36
  • 4h 03m
  • Direct
  • American Airlines (AA 2285)Boeing 737 Max 8 Passenger
  • American Airlines (AA 2285)
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • Boeing 737 Max 8 Passenger
  • 11:34 SNA
    17:37 ORD
    4Hrs, 03m Direct
  • SNASanta Ana John Wayne Airport 11:34 - ORD 17:37 4h 03m Direct
  • SNASanta Ana John Wayne Airport 11:34
  • ORDChicago O'Hare International Airport 17:37
  • 4h 03m
  • Direct
  • American Airlines (AA 2285)Boeing 737 Max 8 Passenger
  • American Airlines (AA 2285)
    • -
    • -
    • -
    • -
    • F
    • -
    • S
  • Boeing 737 Max 8 Passenger
  • 11:43 SNA
    17:38 ORD
    3Hrs, 55m Direct
  • SNASanta Ana John Wayne Airport 11:43 - ORD 17:38 3h 55m Direct
  • SNASanta Ana John Wayne Airport 11:43
  • ORDChicago O'Hare International Airport 17:38
  • 3h 55m
  • Direct
  • American Airlines (AA 2285)Boeing 737 Max 8 Passenger
  • American Airlines (AA 2285)
    • M
    • T
    • W
    • T
    • -
    • -
    • -
  • Boeing 737 Max 8 Passenger
  • 12:55 SNA
    22:35 ORD
    7Hrs, 40m Direct
  • SNASanta Ana John Wayne Airport 12:55 - ORD 22:35 7h 40m Direct
  • SNASanta Ana John Wayne Airport 12:55
  • ORDChicago O'Hare International Airport 22:35
  • 7h 40m
  • Direct
  • Southwest Airlines (WN 3010)Boeing 737 700
  • Southwest Airlines (WN 3010)
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • Boeing 737 700
  • 13:10 SNA
    19:15 ORD
    4Hrs, 05m Direct
  • SNASanta Ana John Wayne Airport 13:10 - ORD 19:15 4h 05m Direct
  • SNASanta Ana John Wayne Airport 13:10
  • ORDChicago O'Hare International Airport 19:15
  • 4h 05m
  • Direct
  • American Airlines (AA 2212)Boeing 737 Max 8 Passenger
  • American Airlines (AA 2212)
    • -
    • -
    • -
    • -
    • F
    • -
    • S
  • Boeing 737 Max 8 Passenger
  • 13:34 SNA
    19:32 ORD
    3Hrs, 58m Direct
  • SNASanta Ana John Wayne Airport 13:34 - ORD 19:32 3h 58m Direct
  • SNASanta Ana John Wayne Airport 13:34
  • ORDChicago O'Hare International Airport 19:32
  • 3h 58m
  • Direct
  • American Airlines (AA 2212)Boeing 737 Max 8 Passenger
  • American Airlines (AA 2212)
    • M
    • T
    • W
    • T
    • -
    • -
    • -
  • Boeing 737 Max 8 Passenger
  • 14:12 SNA
    20:20 ORD
    4Hrs, 08m Direct
  • SNASanta Ana John Wayne Airport 14:12 - ORD 20:20 4h 08m Direct
  • SNASanta Ana John Wayne Airport 14:12
  • ORDChicago O'Hare International Airport 20:20
  • 4h 08m
  • Direct
  • United Airlines (UA 1641)Boeing 737 Max 8 Passenger
  • United Airlines (UA 1641)
    • M
    • T
    • W
    • T
    • F
    • S
    • S
  • Boeing 737 Max 8 Passenger
  • 14:28 SNA
    20:34 ORD
    4Hrs, 06m Direct
  • SNASanta Ana John Wayne Airport 14:28 - ORD 20:34 4h 06m Direct
  • SNASanta Ana John Wayne Airport 14:28
  • ORDChicago O'Hare International Airport 20:34
  • 4h 06m
  • Direct
  • American Airlines (AA 2212)Boeing 737 Max 8 Passenger
  • American Airlines (AA 2212)
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • Boeing 737 Max 8 Passenger
  • 15:23 SNA
    21:27 ORD
    4Hrs, 04m Direct
  • SNASanta Ana John Wayne Airport 15:23 - ORD 21:27 4h 04m Direct
  • SNASanta Ana John Wayne Airport 15:23
  • ORDChicago O'Hare International Airport 21:27
  • 4h 04m
  • Direct
  • American Airlines (AA 1674)Boeing 737 800
  • American Airlines (AA 1674)
    • -
    • -
    • -
    • -
    • F
    • -
    • S
  • Boeing 737 800
  • 15:50 SNA
    23:05 MDW
    5Hrs, 15m Direct
  • SNASanta Ana John Wayne Airport 15:50 - MDW 23:05 5h 15m Direct
  • SNASanta Ana John Wayne Airport 15:50
  • MDWChicago Midway Airport 23:05
  • 5h 15m
  • Direct
  • Southwest Airlines (WN 3274)Boeing 737 700
  • Southwest Airlines (WN 3274)
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • Boeing 737 700
  • 16:20 SNA
    23:55 ORD
    5Hrs, 35m Direct
  • SNASanta Ana John Wayne Airport 16:20 - ORD 23:55 5h 35m Direct
  • SNASanta Ana John Wayne Airport 16:20
  • ORDChicago O'Hare International Airport 23:55
  • 5h 35m
  • Direct
  • Southwest Airlines (WN 2359)Boeing 737 700
  • Southwest Airlines (WN 2359)
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • Boeing 737 700
No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
What’s the fastest flight time from Santa Ana to Chicago?

The fastest flight time for direct flights from Santa Ana to Chicago is 3 hours 55 minutes. Check latest flight schedules & prices on Wego.

How far is Chicago from Santa Ana?

The flight distance between Santa Ana and Chicago is 2789km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 07:00. The last flight of the day departs at 07:00. See the full list of flight times on Wego.

How many airlines offer direct flights from Santa Ana to Chicago?

There are 3 airlines that offer direct flights from Santa Ana to Chicago. Find out the list of airlines on Wego.