Flight Schedules

Last Updated: Mon, 2 Dec, 2024

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  • 18:40 DSM
    20:19 ORD
    1Hrs, 39m Direct
  • DSMDes Moines Airport 18:40 - ORD 20:19 1h 39m Direct
  • DSMDes Moines Airport 18:40
  • ORDChicago O'Hare International Airport 20:19
  • 1h 39m
  • Direct
  • United Airlines (UA 4571)Canadair Regional Jet 550
  • United Airlines (UA 4571)
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  • Canadair Regional Jet 550
  • 05:45 DSM
    07:23 ORD
    1Hrs, 38m Direct
  • DSMDes Moines Airport 05:45 - ORD 07:23 1h 38m Direct
  • DSMDes Moines Airport 05:45
  • ORDChicago O'Hare International Airport 07:23
  • 1h 38m
  • Direct
  • American Airlines (AA 4857)Crj 700 Canadair Regional
  • American Airlines (AA 4857)
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  • Crj 700 Canadair Regional
  • 05:45 DSM
    07:26 ORD
    1Hrs, 41m Direct
  • DSMDes Moines Airport 05:45 - ORD 07:26 1h 41m Direct
  • DSMDes Moines Airport 05:45
  • ORDChicago O'Hare International Airport 07:26
  • 1h 41m
  • Direct
  • American Airlines (AA 3600)Embraer 170
  • American Airlines (AA 3600)
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  • Embraer 170
  • 05:45 DSM
    07:26 ORD
    1Hrs, 41m Direct
  • DSMDes Moines Airport 05:45 - ORD 07:26 1h 41m Direct
  • DSMDes Moines Airport 05:45
  • ORDChicago O'Hare International Airport 07:26
  • 1h 41m
  • Direct
  • American Airlines (AA 4455)Embraer Emb 175
  • American Airlines (AA 4455)
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  • Embraer Emb 175
  • 05:45 DSM
    07:27 ORD
    1Hrs, 42m Direct
  • DSMDes Moines Airport 05:45 - ORD 07:27 1h 42m Direct
  • DSMDes Moines Airport 05:45
  • ORDChicago O'Hare International Airport 07:27
  • 1h 42m
  • Direct
  • American Airlines (AA 6075)Crj Canadair Regional
  • American Airlines (AA 6075)
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  • Crj Canadair Regional
  • 08:00 DSM
    09:35 ORD
    1Hrs, 35m Direct
  • DSMDes Moines Airport 08:00 - ORD 09:35 1h 35m Direct
  • DSMDes Moines Airport 08:00
  • ORDChicago O'Hare International Airport 09:35
  • 1h 35m
  • Direct
  • United Airlines (UA 1363)Airbus
  • United Airlines (UA 1363)
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  • Airbus
  • 08:00 DSM
    09:35 ORD
    1Hrs, 35m Direct
  • DSMDes Moines Airport 08:00 - ORD 09:35 1h 35m Direct
  • DSMDes Moines Airport 08:00
  • ORDChicago O'Hare International Airport 09:35
  • 1h 35m
  • Direct
  • United Airlines (UA 1363)Boeing 737 900
  • United Airlines (UA 1363)
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  • Boeing 737 900
  • 11:29 DSM
    13:06 ORD
    1Hrs, 37m Direct
  • DSMDes Moines Airport 11:29 - ORD 13:06 1h 37m Direct
  • DSMDes Moines Airport 11:29
  • ORDChicago O'Hare International Airport 13:06
  • 1h 37m
  • Direct
  • United Airlines (UA 4405)Canadair Regional Jet 550
  • United Airlines (UA 4405)
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  • Canadair Regional Jet 550
  • 11:58 DSM
    13:40 ORD
    1Hrs, 42m Direct
  • DSMDes Moines Airport 11:58 - ORD 13:40 1h 42m Direct
  • DSMDes Moines Airport 11:58
  • ORDChicago O'Hare International Airport 13:40
  • 1h 42m
  • Direct
  • American Airlines (AA 6062)Crj Canadair Regional
  • American Airlines (AA 6062)
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  • Crj Canadair Regional
  • 12:00 DSM
    13:41 ORD
    1Hrs, 41m Direct
  • DSMDes Moines Airport 12:00 - ORD 13:41 1h 41m Direct
  • DSMDes Moines Airport 12:00
  • ORDChicago O'Hare International Airport 13:41
  • 1h 41m
  • Direct
  • American Airlines (AA 4753)Embraer Emb 175
  • American Airlines (AA 4753)
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  • Embraer Emb 175
  • 15:11 DSM
    16:48 ORD
    1Hrs, 37m Direct
  • DSMDes Moines Airport 15:11 - ORD 16:48 1h 37m Direct
  • DSMDes Moines Airport 15:11
  • ORDChicago O'Hare International Airport 16:48
  • 1h 37m
  • Direct
  • United Airlines (UA 4189)Canadair Regional Jet 550
  • United Airlines (UA 4189)
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  • Canadair Regional Jet 550
  • 15:56 DSM
    17:39 ORD
    1Hrs, 43m Direct
  • DSMDes Moines Airport 15:56 - ORD 17:39 1h 43m Direct
  • DSMDes Moines Airport 15:56
  • ORDChicago O'Hare International Airport 17:39
  • 1h 43m
  • Direct
  • American Airlines (AA 4570)Embraer Emb 175
  • American Airlines (AA 4570)
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  • Embraer Emb 175
  • 16:00 DSM
    17:44 ORD
    1Hrs, 44m Direct
  • DSMDes Moines Airport 16:00 - ORD 17:44 1h 44m Direct
  • DSMDes Moines Airport 16:00
  • ORDChicago O'Hare International Airport 17:44
  • 1h 44m
  • Direct
  • American Airlines (AA 5996)Er4 Embraer Rj145 Amazon
  • American Airlines (AA 5996)
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  • Er4 Embraer Rj145 Amazon
  • 16:00 DSM
    17:32 ORD
    1Hrs, 32m Direct
  • DSMDes Moines Airport 16:00 - ORD 17:32 1h 32m Direct
  • DSMDes Moines Airport 16:00
  • ORDChicago O'Hare International Airport 17:32
  • 1h 32m
  • Direct
  • American Airlines (AA 3554)Embraer 170
  • American Airlines (AA 3554)
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  • Embraer 170
  • 18:45 DSM
    23:05 MDW
    4Hrs, 20m 1 Stop (STL)
  • DSMDes Moines Airport 18:45 - MDW 23:05 4h 20m 1 Stop (STL) Saint Louis
  • DSMDes Moines Airport 18:45
    STLSt Louis Lambert Intl Airport 21:55
  • STLSt Louis Lambert Intl Airport 19:50
    MDWChicago Midway Airport 23:05
  • 4h 20m (2h 05m)
  • 1 Stop STL · Saint Louis 2h 05m
  • Southwest Airlines (WN 372)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 2364)Boeing 737 Max 8 Passenger
  • Southwest Airlines (WN 372)
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  • 05:30 DSM
    09:25 MDW
    3Hrs, 55m 1 Stop (STL)
  • DSMDes Moines Airport 05:30 - MDW 09:25 3h 55m 1 Stop (STL) Saint Louis
  • DSMDes Moines Airport 05:30
    STLSt Louis Lambert Intl Airport 08:15
  • STLSt Louis Lambert Intl Airport 06:50
    MDWChicago Midway Airport 09:25
  • 3h 55m (1h 25m)
  • 1 Stop STL · Saint Louis 1h 25m
  • Southwest Airlines (WN 372)Boeing 737 700
    Southwest Airlines (WN 498)Boeing 737 700
  • Southwest Airlines (WN 372)
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  • 06:50 DSM
    11:50 MDW
    5Hrs, 00m 1 Stop (STL)
  • DSMDes Moines Airport 06:50 - MDW 11:50 5h 1 Stop (STL) Saint Louis
  • DSMDes Moines Airport 06:50
    STLSt Louis Lambert Intl Airport 10:40
  • STLSt Louis Lambert Intl Airport 08:05
    MDWChicago Midway Airport 11:50
  • 5h (2h 35m)
  • 1 Stop STL · Saint Louis 2h 35m
  • Southwest Airlines (WN 372)Boeing 737 700
    Southwest Airlines (WN 2364)Boeing 737 800
  • Southwest Airlines (WN 372)
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  • 16:10 DSM
    20:05 MDW
    3Hrs, 55m 1 Stop (STL)
  • DSMDes Moines Airport 16:10 - MDW 20:05 3h 55m 1 Stop (STL) Saint Louis
  • DSMDes Moines Airport 16:10
    STLSt Louis Lambert Intl Airport 18:55
  • STLSt Louis Lambert Intl Airport 17:15
    MDWChicago Midway Airport 20:05
  • 3h 55m (1h 40m)
  • 1 Stop STL · Saint Louis 1h 40m
  • Southwest Airlines (WN 2925)Boeing 737 800
    Southwest Airlines (WN 1253)Boeing 737 700
  • Southwest Airlines (WN 2925)
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No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
What’s the fastest flight time from Des Moines to Chicago?

The fastest flight time for direct flights from Des Moines to Chicago is 1 hour 32 minutes. Check latest flight schedules & prices on Wego.

What’s the most popular airline flying from Des Moines to Chicago?

The most popular airline flying from Des Moines to Chicago is American Airlines. Find the latest flight deals on Wego.

How far is Chicago from Des Moines?

The flight distance between Des Moines and Chicago is 497km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 05:30. The last flight of the day departs at 18:40. See the full list of flight times on Wego.

How many airlines offer direct flights from Des Moines to Chicago?

There are 2 airlines that offer direct flights from Des Moines to Chicago. Find out the list of airlines on Wego.